Proton MR spectroscopy of Wernicke encephalopathy.
نویسندگان
چکیده
Two patients with acute thiamine deficiency were examined with thalamic single-voxel proton MR spectroscopy. T2-weighted images exhibited increased signal intensity. N-acetylaspartate (NAA)/creatine (Cr) ratios were low without detectable lactate. Owing to substantially decreased choline (Cho) T2, the Cho/Cr ratio was not decreased. After thiamine therapy, the NAA/Cr ratio increased, paralleling clinical improvement and reduction in the areas of signal-intensity changes.
منابع مشابه
Proton MR spectroscopy in Wernicke encephalopathy.
Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent wi...
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ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 23 10 شماره
صفحات -
تاریخ انتشار 2002